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Journal:Proteins:3
From Proteopedia
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''Never Born'' proteins are random polypeptides with amino acid content similar to that of native proteins. | ''Never Born'' proteins are random polypeptides with amino acid content similar to that of native proteins. | ||
| + | |||
| + | Can recently developed AI/Deep Learning tools for predicting 3D protein structures like: | ||
| + | * AlphaFold2 (AF2) | ||
| + | * RoseTTAFold (RTF) | ||
| + | * Evolutionary Scale Modeling (ESM-2) | ||
| + | be useful to see if ''Newly Born'' proteins are similar to ''Never Born'' proteins? | ||
Revision as of 14:35, 3 May 2023
Do Newly Born orphan proteins resemble Never Born proteins? A study using three deep learning algorithms
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
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