4kxw
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='4kxw' size='340' side='right'caption='[[4kxw]], [[Resolution|resolution]] 0.97Å' scene=''> | <StructureSection load='4kxw' size='340' side='right'caption='[[4kxw]], [[Resolution|resolution]] 0.97Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4kxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4kxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KXW FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DX5:D-XYLITOL-5-PHOSPHATE'>DX5</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DX5:D-XYLITOL-5-PHOSPHATE'>DX5</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TKT ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Transketolase Transketolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.1 2.2.1.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxw OCA], [https://pdbe.org/4kxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kxw RCSB], [https://www.ebi.ac.uk/pdbsum/4kxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxw ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxw OCA], [https://pdbe.org/4kxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kxw RCSB], [https://www.ebi.ac.uk/pdbsum/4kxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/TKT_HUMAN TKT_HUMAN] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 22: | Line 20: | ||
==See Also== | ==See Also== | ||
| - | *[[Transketolase|Transketolase]] | + | *[[Transketolase 3D structures|Transketolase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Ficner R]] | |
| - | [[Category: Ficner | + | [[Category: Luedtke S]] |
| - | [[Category: Luedtke | + | [[Category: Neumann P]] |
| - | [[Category: Neumann | + | [[Category: Tittmann K]] |
| - | [[Category: Tittmann | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 07:22, 10 May 2023
Human transketolase in covalent complex with donor ketose D-xylulose-5-phosphate, crystal 2
| |||||||||||
