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4z29

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Revision as of 07:35, 10 May 2023

Crystal structure of the magnetobacterial protein MtxA C-terminal domain

Structural highlights

4z29 is a 2 chain structure with sequence from Magnetospirillum gryphiswaldense. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

A4TUL6_9PROT

Publication Abstract from PubMed

Magnetotactic bacteria (MTB) are a diverse group of aquatic bacteria that have the magnetotaxis ability to align themselves along the geomagnetic field lines and to navigate to a microoxic zone at the bottom of chemically stratified natural water. This special navigation is the result of a unique linear assembly of a specialized organelle, the magnetosome, which contains a biomineralized magnetic nanocrystal enveloped by a cytoplasmic membrane. The Magnetospirillum gryphiswaldense MtxA protein (MGR_0208) was suggested to play a role in bacterial magnetotaxis due to its gene location in an operon together with putative signal transduction genes. Since no homology is found for MtxA, and to better understand the role and function of MtxA in MTBes magnetotaxis, we initiated structural and functional studies of MtxA via X-ray crystallography and deletion mutagenesis. Here, we present the crystal structure of the MtxA C-terminal domain and provide new insights into its sequence-structure relationship.

Crystal structure of the magnetobacterial protein MtxA C-terminal domain reveals a new sequence-structure relationship.,Davidov G, Muller FD, Baumgartner J, Bitton R, Faivre D, Schuler D, Zarivach R Front Mol Biosci. 2015 May 21;2:25. doi: 10.3389/fmolb.2015.00025. eCollection, 2015. PMID:26052516^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Davidov G, Muller FD, Baumgartner J, Bitton R, Faivre D, Schuler D, Zarivach R. Crystal structure of the magnetobacterial protein MtxA C-terminal domain reveals a new sequence-structure relationship. Front Mol Biosci. 2015 May 21;2:25. doi: 10.3389/fmolb.2015.00025. eCollection, 2015. PMID:26052516 doi:http://dx.doi.org/10.3389/fmolb.2015.00025

1 Structural highlights
2 Function
3 Publication Abstract from PubMed
4 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4z29"

Categories: Large Structures | Magnetospirillum gryphiswaldense | Davidov G | Zarivach R

@@ Line 3: / Line 3: @@
 <StructureSection load='4z29' size='340' side='right'caption='[[4z29]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4z29]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_6361 Dsm 6361]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z29 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4z29]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetospirillum_gryphiswaldense Magnetospirillum gryphiswaldense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z29 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Z29 FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mtxA, MGR_0208 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=55518 DSM 6361])</td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4z29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z29 OCA], [https://pdbe.org/4z29 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4z29 RCSB], [https://www.ebi.ac.uk/pdbsum/4z29 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4z29 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z29 OCA], [http://pdbe.org/4z29 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z29 RCSB], [http://www.ebi.ac.uk/pdbsum/4z29 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z29 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/A4TUL6_9PROT A4TUL6_9PROT]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 20: / Line 21: @@
 __TOC__
 </StructureSection>
-[[Category: Dsm 6361]]
 [[Category: Large Structures]]
-[[Category: Davidov, G]]
+[[Category: Magnetospirillum gryphiswaldense]]
-[[Category: Zarivach, R]]
+[[Category: Davidov G]]
-[[Category: Big]]
+[[Category: Zarivach R]]
-[[Category: Mtxa]]
-[[Category: Signaling protein]]
-[[Category: Tpr]]

4z29

From Proteopedia

Revision as of 07:35, 10 May 2023

Crystal structure of the magnetobacterial protein MtxA C-terminal domain

Structural highlights

Function

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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