7xs6

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'''Unreleased structure'''
 
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The entry 7xs6 is ON HOLD until Paper Publication
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==structure of a membrane-integrated glycosyltransferase with inhibitor==
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<StructureSection load='7xs6' size='340' side='right'caption='[[7xs6]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7xs6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XS6 FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0V9:(19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl+(9Z)-hexadec-9-enoate'>0V9</scene>, <scene name='pdbligand=BGI:(2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]acetic+acid+(non-preferred+name)'>BGI</scene>, <scene name='pdbligand=C14:TETRADECANE'>C14</scene>, <scene name='pdbligand=D12:DODECANE'>D12</scene>, <scene name='pdbligand=HP6:HEPTANE'>HP6</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xs6 OCA], [https://pdbe.org/7xs6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xs6 RCSB], [https://www.ebi.ac.uk/pdbsum/7xs6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xs6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CHS1_YEAST CHS1_YEAST] Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer (PubMed:2941152). Required for mitotic division septum formation during adverse conditions (PubMed:2523889).<ref>PMID:2523889</ref> <ref>PMID:2941152</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Ding XY]]
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[[Category: Liu XT]]
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[[Category: Wu YN]]
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[[Category: Yang YZ]]
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[[Category: Yu HJ]]
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[[Category: Zhang M]]
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[[Category: Zhang MJ]]

Revision as of 06:56, 18 May 2023

structure of a membrane-integrated glycosyltransferase with inhibitor

PDB ID 7xs6

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OCA

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