7zsr

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'''Unreleased structure'''
 
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The entry 7zsr is ON HOLD until Paper Publication
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==purine nucleoside phosphorylase in complex with JS-379==
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<StructureSection load='7zsr' size='340' side='right'caption='[[7zsr]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
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Authors: Djukic, S., Pachl, P., Rezacova, P.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7zsr]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZSR FirstGlance]. <br>
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Description: purine nucleoside phosphorylase in complex with JS-379
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=JSI:[(~{E})-2-[5-bromanyl-2-[(4-oxidanylidene-3,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)sulfanyl]phenyl]ethenyl]phosphonic+acid'>JSI</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zsr OCA], [https://pdbe.org/7zsr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zsr RCSB], [https://www.ebi.ac.uk/pdbsum/7zsr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zsr ProSAT]</span></td></tr>
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[[Category: Rezacova, P]]
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</table>
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[[Category: Pachl, P]]
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== Function ==
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[[Category: Djukic, S]]
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[https://www.uniprot.org/uniprot/A0A045IAS2_MYCTX A0A045IAS2_MYCTX] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.[ARBA:ARBA00002678]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Djukic S]]
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[[Category: Pachl P]]
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[[Category: Rezacova P]]

Revision as of 06:57, 18 May 2023

purine nucleoside phosphorylase in complex with JS-379

PDB ID 7zsr

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