4znk
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='4znk' size='340' side='right'caption='[[4znk]], [[Resolution|resolution]] 1.93Å' scene=''> | <StructureSection load='4znk' size='340' side='right'caption='[[4znk]], [[Resolution|resolution]] 1.93Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4znk]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4znk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_virus_P74-26 Thermus virus P74-26]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZNK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZNK FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4znk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4znk OCA], [https://pdbe.org/4znk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4znk RCSB], [https://www.ebi.ac.uk/pdbsum/4znk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4znk ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A7XXR1_BP742 A7XXR1_BP742] The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome to initiate and to end a packaging reaction. The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (packaging sequence), and a large terminase subunit possessing endonucleolytic and ATPase activities. Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine. The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer. Once the capsid is packaged with the DNA, the terminase complex is substituted by the tail.[HAMAP-Rule:MF_04146] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 20: | ||
==See Also== | ==See Also== | ||
| - | *[[Terminase|Terminase]] | + | *[[Terminase 3D Structures|Terminase 3D Structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
| Line 26: | Line 26: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Thermus | + | [[Category: Thermus virus P74-26]] |
| - | [[Category: Duffy | + | [[Category: Duffy CM]] |
| - | [[Category: Hayes | + | [[Category: Hayes JA]] |
| - | [[Category: Hilbert | + | [[Category: Hilbert BJ]] |
| - | [[Category: Kelch | + | [[Category: Kelch BA]] |
| - | [[Category: Stone | + | [[Category: Stone NP]] |
| - | + | ||
| - | + | ||
Revision as of 07:34, 18 May 2023
Thermus Phage P74-26 Large Terminase ATPase domain from (P 32 2 1 space group)
| |||||||||||
