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4zt6
From Proteopedia
(Difference between revisions)
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<StructureSection load='4zt6' size='340' side='right'caption='[[4zt6]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='4zt6' size='340' side='right'caption='[[4zt6]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4zt6]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4zt6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZT6 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4RD:N-[(4R)-6,8-DICHLORO-3,4-DIHYDRO-2H-CHROMEN-4-YL]-N-(5-FLUORO-1H-IMIDAZO[4,5-B]PYRIDIN-2-YL)PROPANE-1,3-DIAMINE'>4RD</scene>, <scene name='pdbligand= | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4RD:N-[(4R)-6,8-DICHLORO-3,4-DIHYDRO-2H-CHROMEN-4-YL]-N-(5-FLUORO-1H-IMIDAZO[4,5-B]PYRIDIN-2-YL)PROPANE-1,3-DIAMINE'>4RD</scene>, <scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zt6 OCA], [https://pdbe.org/4zt6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zt6 RCSB], [https://www.ebi.ac.uk/pdbsum/4zt6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zt6 ProSAT]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q38C91_TRYB2 Q38C91_TRYB2] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Trypanosoma brucei brucei TREU927]] |
| - | + | [[Category: Hol WGJ]] | |
| - | [[Category: Hol | + | [[Category: Koh C-Y]] |
| - | [[Category: Koh | + | |
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Revision as of 07:40, 18 May 2023
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-[(4R)-6,8-dichloro-3,4-dihydro-2H-chromen-4-yl]-N'-(5-fluoro-1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1709)
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