8ejk

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'''Unreleased structure'''
 
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The entry 8ejk is ON HOLD until Paper Publication
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==Structure of FFAR1-Gq complex bound to TAK-875 in a lipid nanodisc==
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<StructureSection load='8ejk' size='340' side='right'caption='[[8ejk]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8ejk]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EJK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EJK FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2YB:[(3S)-6-({2,6-DIMETHYL-4-[3-(METHYLSULFONYL)PROPOXY]BIPHENYL-3-YL}METHOXY)-2,3-DIHYDRO-1-BENZOFURAN-3-YL]ACETIC+ACID'>2YB</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ejk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ejk OCA], [https://pdbe.org/8ejk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ejk RCSB], [https://www.ebi.ac.uk/pdbsum/8ejk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ejk ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chapman K]]
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[[Category: Inoue A]]
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[[Category: Kumari P]]
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[[Category: Lian P]]
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[[Category: Rosenbaum DM]]

Revision as of 04:04, 25 May 2023

Structure of FFAR1-Gq complex bound to TAK-875 in a lipid nanodisc

PDB ID 8ejk

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