5a43

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Current revision (04:38, 25 May 2023) (edit) (undo)
 
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<StructureSection load='5a43' size='340' side='right'caption='[[5a43]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
<StructureSection load='5a43' size='340' side='right'caption='[[5a43]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5a43]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Eco45 Eco45] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A43 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A43 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5a43]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_S88 Escherichia coli S88] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A43 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMU:DECYL-BETA-D-MALTOPYRANOSIDE'>DMU</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMU:DECYL-BETA-D-MALTOPYRANOSIDE'>DMU</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a43 OCA], [https://pdbe.org/5a43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a43 RCSB], [https://www.ebi.ac.uk/pdbsum/5a43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a43 ProSAT]</span></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a40|5a40]], [[5a41|5a41]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a43 OCA], [http://pdbe.org/5a43 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a43 RCSB], [http://www.ebi.ac.uk/pdbsum/5a43 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a43 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/B7LI20_ECO45 B7LI20_ECO45]] Important for reducing fluoride concentration in the cell, thus reducing its toxicity.[HAMAP-Rule:MF_00454][SAAS:SAAS00096000]
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[https://www.uniprot.org/uniprot/B7LI20_ECO45 B7LI20_ECO45] Important for reducing fluoride concentration in the cell, thus reducing its toxicity.[HAMAP-Rule:MF_00454][SAAS:SAAS00096000]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Eco45]]
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[[Category: Escherichia coli S88]]
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Koide, A]]
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[[Category: Koide A]]
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[[Category: Koide, S]]
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[[Category: Koide S]]
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[[Category: Kolmakova-Partensky, L]]
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[[Category: Kolmakova-Partensky L]]
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[[Category: Miller, C]]
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[[Category: Miller C]]
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[[Category: Newstead, S]]
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[[Category: Newstead S]]
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[[Category: Shane, T]]
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[[Category: Shane T]]
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[[Category: Stockbridge, R B]]
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[[Category: Stockbridge RB]]
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[[Category: Ec2]]
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[[Category: Fluc]]
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[[Category: Fluoride ion channel]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of a dual topology fluoride ion channel.

PDB ID 5a43

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