Indole-3-glycerol phosphate synthase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:33, 29 May 2023) (edit) (undo)
 
Line 8: Line 8:
==3D structures of IGPS==
==3D structures of IGPS==
-
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+
[[IGPS 3D structures]]
-
{{#tree:id=OrganizedByTopic|openlevels=0|
+
-
 
+
-
*Indole-3-glycerol phosphate synthase
+
-
 
+
-
**[[1ox4]], [[1ox6]] – yIGPS HISHF amidotransferase+cyclase domains 1-552 + Ni + PP - yeast<br />
+
-
**[[1igs]], [[3tc6]], [[3tc7]] – SsIGPS + PO4 – ''Sulfolobus solfataricus'' <br />
+
-
**[[5aou]] – SsIGPS (mutant) + PO4 <br />
+
-
**[[5k7j]] – SsIGPS + Zn <br />
+
-
**[[5an7]] – SsIGPS + PO4 + inhibitor<br />
+
-
**[[1juk]], [[2c3z]], [[3nyz]] – SsIGPS + SO4 <br />
+
-
**[[6nw4]] – SsIGPS + SO4 + nitrobenzotriazole<br />
+
-
**[[4iww]] – SsIGPS (mutant) + SO4 + Co<br />
+
-
**[[4ix0]] – SsIGPS (mutant) + SO4 + Ni<br />
+
-
**[[1jul]] – SsIGPS <br />
+
-
**[[4a2r]], [[4a2s]], [[4a29]] - SsIGPS TIM-barrel fold (mutant) <br />
+
-
**[[1j5t]], [[2w6r]] – TmIGPS – ''Thermotoga maritima'' <br />
+
-
**[[1i4n]] – TmIGPS + SO4 <br />
+
-
**[[4j9j]] – TmIGPS subunit HISF (mutant) <br />
+
-
**[[1vh7]], [[2a0n]] – TmIGPS subunit HISF + PO4 <br />
+
-
**[[4fx7]], [[5tql]], [[6vdg]] – TmIGPS subunit HISF (mutant) + PO4 <br />
+
-
**[[3og3]] – TmIGPS subunit HISF (mutant) + SO4 <br />
+
-
**[[3zr4]] – TmIGPS subunits HISF+HISH + Gln <br />
+
-
**[[6ymu]] – TmIGPS subunits HISF+HISH + Phe derivative <br />
+
-
**[[6rtz]], [[6ru0]] – TmIGPS subunits HISF+HISH + PO4 <br />
+
-
**[[2wjz]] – TmIGPS subunits HISF+HISH (mutant) + PO4 <br />
+
-
**[[1vc4]] – IGPS + SO4 – ''Thermus thermophilus''<br />
+
-
**[[3qja]] – MtGPS + SO4 – ''Mycobacterium tuberculosis''<br />
+
-
**[[4fb7]] – MtIGPS <br />
+
-
**[[3tsm]] – IGPS + SO4 – ''Brucella melitensis''<br />
+
-
**[[6bma]] – IGPS + PO4 – ''Campylobacter jejuni''<br />
+
-
**[[4gud]] – IGPS subunit HISH – ''Vibrio cholerae'' <br />
+
-
 
+
-
*IGPS complex with reactants or derivatives
+
-
 
+
-
**[[1ox4]] – yIGPS HISHF amidotransferase+cyclase domains (mutant) + Ni + imidazole derivative<br />
+
-
**[[1a53]] – SsIGPS + IGP <br />
+
-
**[[1lbf]], [[1lbl]] – SsIGPS + CDRP <br />
+
-
**[[3nz1]] – SsIGPS (mutant) + SO4 + transition state analog<br />
+
-
**[[3t40]] – MtIGPS + CPG <br />
+
-
**[[3t44]] – MtIGPS + IGP + anthranilate<br />
+
-
**[[3t55]] – MtIGPS + PMBA <br />
+
-
**[[3t78]] – MtIGPS + fluoroanthranilate<br />
+
-
**[[1jcm]] – EcIGPS N terminal + CDRP derivative – ''Escherichia coli''<br />
+
-
**[[4ewn]] – TmIGPS subunit HISF (mutant) + rCdRP <br />
+
-
**[[6y88]] – IGPS + rCdRP – ''Pseudomonas aeruginosa''<br />
+
-
}}
+
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Structure of IGPS complex with IGP (PDB entry 1a53)

Drag the structure with the mouse to rotate

3D structures of IGPS

IGPS 3D structures

References

  1. Creighton TE, Yanofsky C. Indole-3-glycerol phosphate synthetase of Escherichia coli, an enzyme of the tryptophan operon. J Biol Chem. 1966 Oct 25;241(20):4616-24. PMID:5332729
  2. Hennig M, Darimont BD, Jansonius JN, Kirschner K. The catalytic mechanism of indole-3-glycerol phosphate synthase: crystal structures of complexes of the enzyme from Sulfolobus solfataricus with substrate analogue, substrate, and product. J Mol Biol. 2002 Jun 7;319(3):757-66. PMID:12054868 doi:http://dx.doi.org/10.1016/S0022-2836(02)00378-9

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Personal tools