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| - | | + | #REDIRECT [[8g1n]] This PDB entry is obsolete and replaced by 8g1n |
| - | ==Structure of Campylobacter concisus PglC I57M/Q175M variant==
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| - | <StructureSection load='5w7l' size='340' side='right'caption='[[5w7l]], [[Resolution|resolution]] 2.74Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[5w7l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Camc1 Camc1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W7L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W7L FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEF:DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE'>PEF</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pglC, CCC13826_0450 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=360104 CAMC1])</td></tr>
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| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Undecaprenyl_phosphate_N,N'-diacetylbacillosamine_1-phosphate_transferase Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.8.36 2.7.8.36] </span></td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w7l OCA], [http://pdbe.org/5w7l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w7l RCSB], [http://www.ebi.ac.uk/pdbsum/5w7l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w7l ProSAT]</span></td></tr>
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| - | </table>
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| - | <div style="background-color:#fffaf0;">
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| - | == Publication Abstract from PubMed ==
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| - | Polyprenol phosphate phosphoglycosyl transferases (PGTs) catalyze the first membrane-committed step in assembly of essential glycoconjugates. Currently there is no structure-function information to describe how monotopic PGTs coordinate the reaction between membrane-embedded and soluble substrates. We describe the structure and mode of membrane association of PglC, a PGT from Campylobacter concisus. The structure reveals a unique architecture, provides mechanistic insight and identifies ligand-binding determinants for PglC and the monotopic PGT superfamily.
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| - | Membrane association of monotopic phosphoglycosyl transferase underpins function.,Ray LC, Das D, Entova S, Lukose V, Lynch AJ, Imperiali B, Allen KN Nat Chem Biol. 2018 May 16. pii: 10.1038/s41589-018-0054-z. doi:, 10.1038/s41589-018-0054-z. PMID:29769739<ref>PMID:29769739</ref>
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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| - | </div>
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| - | <div class="pdbe-citations 5w7l" style="background-color:#fffaf0;"></div>
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| - | == References ==
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| - | <references/>
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Camc1]]
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| - | [[Category: Large Structures]]
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| - | [[Category: Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase]]
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| - | [[Category: Allen, K N]]
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| - | [[Category: Das, D]]
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| - | [[Category: Imperiali, B]]
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| - | [[Category: Ray, L C]]
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| - | [[Category: Membrane protein]]
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| - | [[Category: Monotopic]]
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| - | [[Category: Phosphoglycosyltransferase]]
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