|
|
| Line 3: |
Line 3: |
| | <StructureSection load='5b52' size='340' side='right'caption='[[5b52]], [[Resolution|resolution]] 2.30Å' scene=''> | | <StructureSection load='5b52' size='340' side='right'caption='[[5b52]], [[Resolution|resolution]] 2.30Å' scene=''> |
| | == Structural highlights == | | == Structural highlights == |
| - | <table><tr><td colspan='2'>[[5b52]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Psepk Psepk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B52 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B52 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5b52]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida_KT2440 Pseudomonas putida KT2440]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B52 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PP_3765 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=160488 PSEPK])</td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b52 OCA], [https://pdbe.org/5b52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b52 RCSB], [https://www.ebi.ac.uk/pdbsum/5b52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b52 ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b52 OCA], [http://pdbe.org/5b52 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b52 RCSB], [http://www.ebi.ac.uk/pdbsum/5b52 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b52 ProSAT]</span></td></tr> | + | |
| | </table> | | </table> |
| | + | == Function == |
| | + | [https://www.uniprot.org/uniprot/Q88GF9_PSEPK Q88GF9_PSEPK] |
| | <div style="background-color:#fffaf0;"> | | <div style="background-color:#fffaf0;"> |
| | == Publication Abstract from PubMed == | | == Publication Abstract from PubMed == |
| Line 21: |
Line 22: |
| | </StructureSection> | | </StructureSection> |
| | [[Category: Large Structures]] | | [[Category: Large Structures]] |
| - | [[Category: Psepk]] | + | [[Category: Pseudomonas putida KT2440]] |
| - | [[Category: Nojiri, H]] | + | [[Category: Nojiri H]] |
| - | [[Category: Suzuki-Minakuchi, C]] | + | [[Category: Suzuki-Minakuchi C]] |
| - | [[Category: Nucleoid associated protein]]
| + | |
| - | [[Category: Transcription]]
| + | |
| - | [[Category: Transcriptional regulator]]
| + | |
| Structural highlights
Function
Q88GF9_PSEPK
Publication Abstract from PubMed
H-NS family proteins play key roles in bacterial nucleoid compaction and global transcription. MvaT homologues in Pseudomonas have almost negligible amino acid sequence identity with H-NS, but can complement an hns-related phenotype of Escherichia coli. Here, we report the crystal structure of the N-terminal dimerization/oligomerization domain of TurB, an MvaT homologue in Pseudomonas putida KT2440. Our data identify two dimerization sites; the structure of the central dimerization site is almost the same as the corresponding region of H-NS, whereas the terminal dimerization sites are different. Our results reveal similarities and differences in dimerization and oligomerization mechanisms between H-NS and TurB.
Structural similarities and differences in H-NS family proteins revealed by the N-terminal structure of TurB in Pseudomonas putida KT2440.,Suzuki-Minakuchi C, Kawazuma K, Matsuzawa J, Vasileva D, Fujimoto Z, Terada T, Okada K, Nojiri H FEBS Lett. 2016 Oct 6. doi: 10.1002/1873-3468.12425. PMID:27709616[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Suzuki-Minakuchi C, Kawazuma K, Matsuzawa J, Vasileva D, Fujimoto Z, Terada T, Okada K, Nojiri H. Structural similarities and differences in H-NS family proteins revealed by the N-terminal structure of TurB in Pseudomonas putida KT2440. FEBS Lett. 2016 Oct 6. doi: 10.1002/1873-3468.12425. PMID:27709616 doi:http://dx.doi.org/10.1002/1873-3468.12425
|
