7w7o
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The crystal structure of human Calpain-1 protease core in complex with 14a== |
| - | + | <StructureSection load='7w7o' size='340' side='right'caption='[[7w7o]], [[Resolution|resolution]] 1.59Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7w7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W7O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=06Q:N-[(2S)-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide'>06Q</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=H2S:HYDROSULFURIC+ACID'>H2S</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w7o OCA], [https://pdbe.org/7w7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w7o RCSB], [https://www.ebi.ac.uk/pdbsum/7w7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w7o ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CAN1_HUMAN CAN1_HUMAN] Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rao Z]] | ||
| + | [[Category: Shao M]] | ||
| + | [[Category: Yang H]] | ||
| + | [[Category: Zhao J]] | ||
| + | [[Category: Zhao Y]] | ||
Revision as of 05:34, 7 June 2023
The crystal structure of human Calpain-1 protease core in complex with 14a
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Categories: Homo sapiens | Large Structures | Rao Z | Shao M | Yang H | Zhao J | Zhao Y
