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7xy9
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of secondary alcohol dehydrogenases TbSADH after carrier-free immobilization based on weak intermolecular interactions== | |
| - | + | <StructureSection load='7xy9' size='340' side='right'caption='[[7xy9]], [[Resolution|resolution]] 2.12Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7xy9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoanaerobacter_brockii Thermoanaerobacter brockii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XY9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xy9 OCA], [https://pdbe.org/7xy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xy9 RCSB], [https://www.ebi.ac.uk/pdbsum/7xy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xy9 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/ADH_THEBR ADH_THEBR] Alcohol dehydrogenase with a preference for medium chain secondary alcohols, such as 2-butanol and isopropanol. Has very low activity with primary alcohols, such as ethanol. Under physiological conditions, the enzyme reduces aldehydes and 2-ketones to produce secondary alcohols. Is also active with acetaldehyde and propionaldehyde. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Thermoanaerobacter brockii]] | ||
| + | [[Category: Chen Q]] | ||
| + | [[Category: Li X]] | ||
| + | [[Category: Qu G]] | ||
| + | [[Category: Sun ZT]] | ||
| + | [[Category: Wang YJ]] | ||
| + | [[Category: Yang F]] | ||
Revision as of 05:35, 7 June 2023
Cryo-EM structure of secondary alcohol dehydrogenases TbSADH after carrier-free immobilization based on weak intermolecular interactions
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Categories: Large Structures | Thermoanaerobacter brockii | Chen Q | Li X | Qu G | Sun ZT | Wang YJ | Yang F
