8cxc

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m (Protected "8cxc" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 8cxc is ON HOLD
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==Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics==
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<StructureSection load='8cxc' size='340' side='right'caption='[[8cxc]], [[Resolution|resolution]] 4.31&Aring;' scene=''>
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Authors: Bandaranayake, A.D., Rupert, P.B., Lin, I., Pilat, K., Ruff, R.O., Friend, D.J., Chan, M.K., Clarke, M., Carter, J., Meshinchi, S., Mehlin, C., Olson, J.M., Strong, R.K., Correnti, C.E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8cxc]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CXC FirstGlance]. <br>
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Description: Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo-main and Engineering of Potent, T cell-engaging Bispecific Therapeutics
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cxc OCA], [https://pdbe.org/8cxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cxc RCSB], [https://www.ebi.ac.uk/pdbsum/8cxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cxc ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Olson, J.M]]
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== Disease ==
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[[Category: Ruff, R.O]]
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[https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.
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[[Category: Lin, I]]
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== Function ==
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[[Category: Rupert, P.B]]
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[https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Membrane-anchored forms may play a role in cellular adhesion.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref> Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref>
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[[Category: Bandaranayake, A.D]]
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== References ==
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[[Category: Pilat, K]]
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<references/>
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[[Category: Mehlin, C]]
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__TOC__
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[[Category: Strong, R.K]]
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</StructureSection>
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[[Category: Clarke, M]]
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[[Category: Homo sapiens]]
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[[Category: Chan, M.K]]
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[[Category: Large Structures]]
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[[Category: Friend, D.J]]
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[[Category: Mus musculus]]
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[[Category: Carter, J]]
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[[Category: Bandaranayake AD]]
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[[Category: Correnti, C.E]]
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[[Category: Carter J]]
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[[Category: Meshinchi, S]]
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[[Category: Chan MK]]
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[[Category: Clarke M]]
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[[Category: Correnti CE]]
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[[Category: Friend DJ]]
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[[Category: Lin I]]
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[[Category: Mehlin C]]
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[[Category: Meshinchi S]]
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[[Category: Olson JM]]
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[[Category: Pilat K]]
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[[Category: Ruff RO]]
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[[Category: Rupert PB]]
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[[Category: Strong RK]]

Revision as of 05:38, 7 June 2023

Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics

PDB ID 8cxc

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OCA

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