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8dgn
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==14-3-3 epsilon bound to phosphorylated PEAK2 (pS826) peptide== | |
| - | + | <StructureSection load='8dgn' size='340' side='right'caption='[[8dgn]], [[Resolution|resolution]] 3.16Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8dgn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DGN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DGN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dgn OCA], [https://pdbe.org/8dgn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dgn RCSB], [https://www.ebi.ac.uk/pdbsum/8dgn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dgn ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/1433E_HUMAN 1433E_HUMAN] Distal 17p13.3 microdeletion syndrome;17p13.3 microduplication syndrome;Miller-Dieker syndrome. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/1433E_HUMAN 1433E_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hardy JM]] | ||
| + | [[Category: Lucet IS]] | ||
| + | [[Category: Roy MJ]] | ||
Revision as of 05:39, 7 June 2023
14-3-3 epsilon bound to phosphorylated PEAK2 (pS826) peptide
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