7byi

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====
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==Structure of SHMT2 in complex with CBX==
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<StructureSection load='7byi' size='340' side='right'caption='[[7byi]]' scene=''>
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<StructureSection load='7byi' size='340' side='right'caption='[[7byi]], [[Resolution|resolution]] 2.76&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7byi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BYI FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7byi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7byi OCA], [https://pdbe.org/7byi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7byi RCSB], [https://www.ebi.ac.uk/pdbsum/7byi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7byi ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBO:CARBENOXOLONE'>CBO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7byi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7byi OCA], [https://pdbe.org/7byi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7byi RCSB], [https://www.ebi.ac.uk/pdbsum/7byi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7byi ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GLYM_HUMAN GLYM_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.<ref>PMID:21876188</ref>
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==See Also==
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*[[Serine hydroxymethyltransferase 3D structures|Serine hydroxymethyltransferase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Chen Y]]
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[[Category: Li L]]
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[[Category: Lu D]]
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[[Category: Su D]]
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[[Category: Zhang C]]

Revision as of 05:44, 7 June 2023

Structure of SHMT2 in complex with CBX

PDB ID 7byi

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