5c5b
From Proteopedia
(Difference between revisions)
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<StructureSection load='5c5b' size='340' side='right'caption='[[5c5b]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='5c5b' size='340' side='right'caption='[[5c5b]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5c5b]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5c5b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C5B FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c5b OCA], [https://pdbe.org/5c5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c5b RCSB], [https://www.ebi.ac.uk/pdbsum/5c5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c5b ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| - | == Disease == | ||
| - | [[http://www.uniprot.org/uniprot/DP13B_HUMAN DP13B_HUMAN]] A chromosomal aberration involving APPL2/DIP13B is found in patients with chromosome 22q13.3 deletion syndrome. Translocation t(12;22)(q24.1;q13.3) with SHANK3/PSAP2. | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DP13A_HUMAN DP13A_HUMAN] Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction.<ref>PMID:10490823</ref> <ref>PMID:15016378</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chen | + | [[Category: Chen B]] |
| - | [[Category: Chen | + | [[Category: Chen YJ]] |
| - | + | ||
| - | + | ||
Revision as of 06:20, 7 June 2023
Crystal Structure of Human APPL BAR-PH Heterodimer
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