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7fy8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human FABP1 in complex with 2-[[4-cyclopropyl-5-methyl-3-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]thiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acid== | |
| - | + | <StructureSection load='7fy8' size='340' side='right'caption='[[7fy8]], [[Resolution|resolution]] 2.23Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7fy8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FY8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FY8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=VI9:2-({(3P)-4-cyclopropyl-5-methyl-3-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]thiophen-2-yl}carbamoyl)cyclopent-1-ene-1-carboxylic+acid'>VI9</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fy8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fy8 OCA], [https://pdbe.org/7fy8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fy8 RCSB], [https://www.ebi.ac.uk/pdbsum/7fy8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fy8 ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Benz | + | [https://www.uniprot.org/uniprot/FABPL_HUMAN FABPL_HUMAN] Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. |
| - | [[Category: Obst | + | __TOC__ |
| - | [[Category: Rudolph | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Benz J]] | ||
| + | [[Category: Ehler A]] | ||
| + | [[Category: Obst U]] | ||
| + | [[Category: Richter H]] | ||
| + | [[Category: Rudolph MG]] | ||
Revision as of 08:04, 14 June 2023
Crystal Structure of human FABP1 in complex with 2-[[4-cyclopropyl-5-methyl-3-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]thiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acid
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Categories: Homo sapiens | Large Structures | Benz J | Ehler A | Obst U | Richter H | Rudolph MG
