7g1q

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m (Protected "7g1q" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 7g1q is ON HOLD
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==Crystal Structure of human FABP5 in complex with (1S,2R)-2-[(5-carbamoyl-3-ethoxycarbonyl-4-methyl-2-thienyl)carbamoyl]cyclohexanecarboxylic acid==
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<StructureSection load='7g1q' size='340' side='right'caption='[[7g1q]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
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Authors: Ehler, A., Benz, J., Obst, U., Rudolph, M.G.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7g1q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G1Q FirstGlance]. <br>
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Description: Crystal Structure of human FABP5 in complex with (1S,2R)-2-[(5-carbamoyl-3-ethoxycarbonyl-4-methyl-2-thienyl)carbamoyl]cyclohexanecarboxylic acid
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=IOV:(1R,2S)-2-{[5-carbamoyl-3-(ethoxycarbonyl)-4-methylthiophen-2-yl]carbamoyl}cyclohexane-1-carboxylic+acid'>IOV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g1q OCA], [https://pdbe.org/7g1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g1q RCSB], [https://www.ebi.ac.uk/pdbsum/7g1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g1q ProSAT]</span></td></tr>
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[[Category: Ehler, A]]
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</table>
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[[Category: Benz, J]]
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== Function ==
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[[Category: Obst, U]]
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[https://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.
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[[Category: Rudolph, M.G]]
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Benz J]]
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[[Category: Ehler A]]
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[[Category: Obst U]]
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[[Category: Rudolph MG]]

Revision as of 08:09, 14 June 2023

Crystal Structure of human FABP5 in complex with (1S,2R)-2-[(5-carbamoyl-3-ethoxycarbonyl-4-methyl-2-thienyl)carbamoyl]cyclohexanecarboxylic acid

PDB ID 7g1q

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OCA

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