7qdx

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'''Unreleased structure'''
 
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The entry 7qdx is ON HOLD until Paper Publication
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==bacterial IMPDH chimera==
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<StructureSection load='7qdx' size='340' side='right'caption='[[7qdx]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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Authors: Labesse, G., Gelin, M., Munier-Lehmann, H., Gedeon, A., Haouz, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7qdx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QDX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QDX FirstGlance]. <br>
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Description: bacterial IMPDH chimera
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qdx OCA], [https://pdbe.org/7qdx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qdx RCSB], [https://www.ebi.ac.uk/pdbsum/7qdx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qdx ProSAT]</span></td></tr>
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[[Category: Gedeon, A]]
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</table>
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[[Category: Labesse, G]]
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== Function ==
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[[Category: Munier-Lehmann, H]]
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[https://www.uniprot.org/uniprot/IMDH_ECOLI IMDH_ECOLI] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]<ref>PMID:9341229</ref> [https://www.uniprot.org/uniprot/Q9HXM5_PSEAE Q9HXM5_PSEAE] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
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[[Category: Gelin, M]]
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== References ==
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[[Category: Haouz, A]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Gedeon A]]
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[[Category: Gelin M]]
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[[Category: Haouz A]]
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[[Category: Labesse G]]
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[[Category: Munier-Lehmann H]]

Revision as of 08:09, 14 June 2023

bacterial IMPDH chimera

PDB ID 7qdx

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