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7t5q
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of an Arp2/3 complex mini-branch capped by capping protein (CapZ)== | |
| - | + | <StructureSection load='7t5q' size='340' side='right'caption='[[7t5q]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7t5q]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T5Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t5q OCA], [https://pdbe.org/7t5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t5q RCSB], [https://www.ebi.ac.uk/pdbsum/7t5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t5q ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ARC1A_BOVIN ARC1A_BOVIN] Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity).[UniProtKB:Q8AVT9][UniProtKB:Q92747] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Oryctolagus cuniculus]] | ||
| + | [[Category: Boczkowska M]] | ||
| + | [[Category: Dominguez R]] | ||
| + | [[Category: Rebowski G]] | ||
| + | [[Category: Van Eeuwen T]] | ||
Revision as of 08:10, 14 June 2023
Cryo-EM structure of an Arp2/3 complex mini-branch capped by capping protein (CapZ)
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