8a0z
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Candida auris dihydrofolate reductase complexed with NADPH and pyrimethamine== | |
| - | + | <StructureSection load='8a0z' size='340' side='right'caption='[[8a0z]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8a0z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_auris Candida auris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A0Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A0Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CP6:5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE'>CP6</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a0z OCA], [https://pdbe.org/8a0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a0z RCSB], [https://www.ebi.ac.uk/pdbsum/8a0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a0z ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A0L0P1H8_CANAR A0A0L0P1H8_CANAR] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dias MVB]] | ||
| + | [[Category: Kirkman TK]] | ||
Revision as of 08:13, 14 June 2023
Crystal structure of Candida auris dihydrofolate reductase complexed with NADPH and pyrimethamine
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