1l2n
From Proteopedia
| Line 1: | Line 1: | ||
[[Image:1l2n.jpg|left|200px]] | [[Image:1l2n.jpg|left|200px]] | ||
| - | + | <!-- | |
| - | + | The line below this paragraph, containing "STRUCTURE_1l2n", creates the "Structure Box" on the page. | |
| - | + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | |
| - | + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |
| - | | | + | or leave the SCENE parameter empty for the default display. |
| - | | | + | --> |
| - | + | {{STRUCTURE_1l2n| PDB=1l2n | SCENE= }} | |
| - | + | ||
| - | + | ||
| - | }} | + | |
'''Smt3 Solution Structure''' | '''Smt3 Solution Structure''' | ||
| Line 27: | Line 24: | ||
[[Category: Liao, X.]] | [[Category: Liao, X.]] | ||
[[Category: Sheng, W.]] | [[Category: Sheng, W.]] | ||
| - | [[Category: | + | [[Category: Nmr]] |
| - | [[Category: | + | [[Category: Smt3]] |
| - | [[Category: | + | [[Category: Structure]] |
| - | [[Category: | + | [[Category: Ubiquitin-like protein]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 23:28:25 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 20:28, 2 May 2008
Smt3 Solution Structure
Overview
Smt3 belongs to a growing family of ubiquitin-related proteins involved in posttranslational protein modification. Independent studies demonstrate an essential function of Smt3 in the regulation of nucleocytoplasmic transport, and suggest a role in cell-cycle regulation. Here we report the high-resolution NMR structure of yeast Smt3 in the complex free form. Our comparison of the Smt3 NMR structure with the Smt3 crystal structure in complex with the C-Terminal Ulp1 protease domain revealed large structural differences in the binding surface, which is also involved in the Smt3-Ubc-9 interaction detected by NMR. The structural differences in the region indicate the important functions of conserved residues in less structurally defined sequences.
About this Structure
1L2N is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
Solution structure of a yeast ubiquitin-like protein Smt3: the role of structurally less defined sequences in protein-protein recognitions., Sheng W, Liao X, Protein Sci. 2002 Jun;11(6):1482-91. PMID:12021447 Page seeded by OCA on Fri May 2 23:28:25 2008
