1l3w

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1l3w.gif|left|200px]]
[[Image:1l3w.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1l3w |SIZE=350|CAPTION= <scene name='initialview01'>1l3w</scene>, resolution 3.08&Aring;
+
The line below this paragraph, containing "STRUCTURE_1l3w", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1l3w| PDB=1l3w | SCENE= }}
-
|RELATEDENTRY=[[1ncg|1NCG]], [[1nch|1NCH]], [[1nci|1NCI]], [[1edh|1EDH]], [[1ff5|1FF5]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l3w OCA], [http://www.ebi.ac.uk/pdbsum/1l3w PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1l3w RCSB]</span>
+
-
}}
+
'''C-cadherin Ectodomain'''
'''C-cadherin Ectodomain'''
Line 31: Line 28:
[[Category: Shapiro, L.]]
[[Category: Shapiro, L.]]
[[Category: Wong, E.]]
[[Category: Wong, E.]]
-
[[Category: cadherin]]
+
[[Category: Cadherin]]
-
[[Category: calcium binding]]
+
[[Category: Calcium binding]]
-
[[Category: cell adhesion]]
+
[[Category: Cell adhesion]]
-
[[Category: ectodomain]]
+
[[Category: Ectodomain]]
-
[[Category: extracellular]]
+
[[Category: Extracellular]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 23:30:56 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:57:39 2008''
+

Revision as of 20:30, 2 May 2008

Image:1l3w.gif

Template:STRUCTURE 1l3w

C-cadherin Ectodomain


Overview

Cadherins are transmembrane proteins that mediate adhesion between cells in the solid tissues of animals. Here we present the 3.1 angstrom resolution crystal structure of the whole, functional extracellular domain from C-cadherin, a representative "classical" cadherin. The structure suggests a molecular mechanism for adhesion between cells by classical cadherins, and it provides a new framework for understanding both cis (same cell) and trans (juxtaposed cell) cadherin interactions. The trans adhesive interface is a twofold symmetric interaction defined by a conserved tryptophan side chain at the membrane-distal end of a cadherin molecule from one cell, which inserts into a hydrophobic pocket at the membrane-distal end of a cadherin molecule from the opposing cell.

About this Structure

1L3W is a Single protein structure of sequence from Xenopus laevis. Full crystallographic information is available from OCA.

Reference

C-cadherin ectodomain structure and implications for cell adhesion mechanisms., Boggon TJ, Murray J, Chappuis-Flament S, Wong E, Gumbiner BM, Shapiro L, Science. 2002 May 17;296(5571):1308-13. Epub 2002 Apr 18. PMID:11964443 Page seeded by OCA on Fri May 2 23:30:56 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1l3w"
Personal tools