2lcm

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==NMR structure of S3-4 peptide==
==NMR structure of S3-4 peptide==
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<StructureSection load='2lcm' size='340' side='right'caption='[[2lcm]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2lcm' size='340' side='right'caption='[[2lcm]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2lcm]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LCM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LCM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2lcm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LCM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LCM FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lcm OCA], [https://pdbe.org/2lcm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lcm RCSB], [https://www.ebi.ac.uk/pdbsum/2lcm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lcm ProSAT]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lcm OCA], [https://pdbe.org/2lcm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lcm RCSB], [https://www.ebi.ac.uk/pdbsum/2lcm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lcm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CAC1B_HUMAN CAC1B_HUMAN]] Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
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[https://www.uniprot.org/uniprot/CAC1B_HUMAN CAC1B_HUMAN] Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Darbon, H]]
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[[Category: Darbon H]]
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[[Category: Douzi, B]]
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[[Category: De waar M]]
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[[Category: Waar, M De]]
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[[Category: Douzi B]]
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[[Category: Membrane protein]]
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[[Category: Voltage sensor peptide]]
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Revision as of 08:55, 14 June 2023

NMR structure of S3-4 peptide

PDB ID 2lcm

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