2moc

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==Membrane induced structure of novel human tachykinin Hemokinin-1 (hHK1)==
==Membrane induced structure of novel human tachykinin Hemokinin-1 (hHK1)==
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<StructureSection load='2moc' size='340' side='right'caption='[[2moc]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2moc' size='340' side='right'caption='[[2moc]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2moc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MOC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MOC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2moc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MOC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MOC FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2moc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2moc OCA], [https://pdbe.org/2moc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2moc RCSB], [https://www.ebi.ac.uk/pdbsum/2moc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2moc ProSAT]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2moc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2moc OCA], [https://pdbe.org/2moc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2moc RCSB], [https://www.ebi.ac.uk/pdbsum/2moc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2moc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TKN4_HUMAN TKN4_HUMAN]] Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility.<ref>PMID:12716968</ref> <ref>PMID:17101218</ref> <ref>PMID:17437961</ref> <ref>PMID:17655832</ref>
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[https://www.uniprot.org/uniprot/TKN4_HUMAN TKN4_HUMAN] Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility.<ref>PMID:12716968</ref> <ref>PMID:17101218</ref> <ref>PMID:17437961</ref> <ref>PMID:17655832</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cowsik, S]]
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[[Category: Cowsik S]]
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[[Category: Ganjiwale, A]]
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[[Category: Ganjiwale A]]
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[[Category: Neuropeptide]]
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[[Category: Tachykinin]]
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Revision as of 09:40, 14 June 2023

Membrane induced structure of novel human tachykinin Hemokinin-1 (hHK1)

PDB ID 2moc

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