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2mq1
From Proteopedia
(Difference between revisions)
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==Phosphotyrosine binding domain== | ==Phosphotyrosine binding domain== | ||
| - | <StructureSection load='2mq1' size='340' side='right'caption='[[2mq1 | + | <StructureSection load='2mq1' size='340' side='right'caption='[[2mq1]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2mq1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2mq1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MQ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MQ1 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cbll1, Hakai ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mq1 OCA], [https://pdbe.org/2mq1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mq1 RCSB], [https://www.ebi.ac.uk/pdbsum/2mq1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mq1 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mq1 OCA], [https://pdbe.org/2mq1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mq1 RCSB], [https://www.ebi.ac.uk/pdbsum/2mq1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mq1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/HAKAI_MOUSE HAKAI_MOUSE] Promotes ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation.<ref>PMID:11836526</ref> <ref>PMID:22252131</ref> | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: Jing-Song | + | [[Category: Jing-Song F]] |
| - | [[Category: Mukherjee | + | [[Category: Mukherjee M]] |
| - | [[Category: Sivaraman | + | [[Category: Sivaraman J]] |
| - | + | ||
| - | + | ||
Revision as of 09:42, 14 June 2023
Phosphotyrosine binding domain
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