This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1l5j

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1l5j.gif|left|200px]]
[[Image:1l5j.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1l5j |SIZE=350|CAPTION= <scene name='initialview01'>1l5j</scene>, resolution 2.40&Aring;
+
The line below this paragraph, containing "STRUCTURE_1l5j", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=TRA:ACONITATE+ION'>TRA</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Aconitate_hydratase Aconitate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.3 4.2.1.3] </span>
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1l5j| PDB=1l5j | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l5j OCA], [http://www.ebi.ac.uk/pdbsum/1l5j PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1l5j RCSB]</span>
+
-
}}
+
'''CRYSTAL STRUCTURE OF E. COLI ACONITASE B.'''
'''CRYSTAL STRUCTURE OF E. COLI ACONITASE B.'''
Line 34: Line 31:
[[Category: Tang, Y.]]
[[Category: Tang, Y.]]
[[Category: Williams, C H.]]
[[Category: Williams, C H.]]
-
[[Category: citric acid cycle]]
+
[[Category: Citric acid cycle]]
-
[[Category: heat-like domain]]
+
[[Category: Heat-like domain]]
-
[[Category: molecular recognition]]
+
[[Category: Molecular recognition]]
-
[[Category: rna binding]]
+
[[Category: Rna binding]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 23:33:52 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:58:21 2008''
+

Revision as of 20:33, 2 May 2008

Image:1l5j.gif

Template:STRUCTURE 1l5j

CRYSTAL STRUCTURE OF E. COLI ACONITASE B.


Overview

The major bifunctional aconitase of Escherichia coli (AcnB) serves as either an enzymic catalyst or a mRNA-binding post-transcriptional regulator, depending on the status of its iron sulfur cluster. AcnB represents a large, distinct group of Gram-negative bacterial aconitases that have an altered domain organization relative to mitochondrial aconitase and other aconitases. Here the 2.4 A structure of E. coli AcnB reveals a high degree of conservation at the active site despite its domain reorganization. It also reveals that the additional domain, characteristic of the AcnB subfamily, is a HEAT-like domain, implying a role in protein protein recognition. This domain packs against the remainder of the protein to form a tunnel leading to the aconitase active site, potentially for substrate channeling.

About this Structure

1L5J is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

E. coli aconitase B structure reveals a HEAT-like domain with implications for protein-protein recognition., Williams CH, Stillman TJ, Barynin VV, Sedelnikova SE, Tang Y, Green J, Guest JR, Artymiuk PJ, Nat Struct Biol. 2002 Jun;9(6):447-52. PMID:11992126 Page seeded by OCA on Fri May 2 23:33:52 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1l5j"
Personal tools