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5mpl

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Current revision (10:18, 14 June 2023) (edit) (undo)
 
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==hnRNP A1 RRM2 in complex with 5'-UCAGUU-3' RNA==
==hnRNP A1 RRM2 in complex with 5'-UCAGUU-3' RNA==
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<StructureSection load='5mpl' size='340' side='right'caption='[[5mpl]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='5mpl' size='340' side='right'caption='[[5mpl]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5mpl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MPL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MPL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5mpl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MPL FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5mpg|5mpg]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mpl OCA], [https://pdbe.org/5mpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mpl RCSB], [https://www.ebi.ac.uk/pdbsum/5mpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mpl ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNRNPA1, HNRPA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mpl OCA], [http://pdbe.org/5mpl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mpl RCSB], [http://www.ebi.ac.uk/pdbsum/5mpl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mpl ProSAT]</span></td></tr>
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</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN]] Amyotrophic lateral sclerosis;Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>
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[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Amyotrophic lateral sclerosis;Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN]] Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.<ref>PMID:17229681</ref>
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[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.<ref>PMID:17229681</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Allain, F H.T]]
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[[Category: Allain FH-T]]
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[[Category: Barraud, P]]
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[[Category: Barraud P]]
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[[Category: Hnrnp]]
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[[Category: Rna]]
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[[Category: Rrm]]
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[[Category: Splicing]]
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Current revision

hnRNP A1 RRM2 in complex with 5'-UCAGUU-3' RNA

PDB ID 5mpl

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