5oun

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==NMR solution structure of the external DII domain of Rvb2 from Saccharomyces cerevisiae==
==NMR solution structure of the external DII domain of Rvb2 from Saccharomyces cerevisiae==
-
<StructureSection load='5oun' size='340' side='right'caption='[[5oun]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='5oun' size='340' side='right'caption='[[5oun]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5oun]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OUN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OUN FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5oun]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OUN FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RVB2, TIH2, TIP49B, YPL235W, P1060 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
+
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5oun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oun OCA], [https://pdbe.org/5oun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5oun RCSB], [https://www.ebi.ac.uk/pdbsum/5oun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5oun ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oun OCA], [http://pdbe.org/5oun PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oun RCSB], [http://www.ebi.ac.uk/pdbsum/5oun PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oun ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/RUVB2_YEAST RUVB2_YEAST]] DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes. Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates. The INO80 complex is involved in DNA repair by associating to 'Ser-129' phosphorylated H2A histones as a response to DNA damage. During transcription may recruit SPT15/TBP to the TATA-boxes of involved genes. Required for box C/D and box H/ACA snoRNA accumulation and involved in pre-rRNA processing.<ref>PMID:10787406</ref> <ref>PMID:10952318</ref> <ref>PMID:11278922</ref> <ref>PMID:11604509</ref> <ref>PMID:12576485</ref> <ref>PMID:14645854</ref> <ref>PMID:14690608</ref> <ref>PMID:15045029</ref> <ref>PMID:15525518</ref>
+
[https://www.uniprot.org/uniprot/RUVB2_YEAST RUVB2_YEAST] DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes. Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates. The INO80 complex is involved in DNA repair by associating to 'Ser-129' phosphorylated H2A histones as a response to DNA damage. During transcription may recruit SPT15/TBP to the TATA-boxes of involved genes. Required for box C/D and box H/ACA snoRNA accumulation and involved in pre-rRNA processing.<ref>PMID:10787406</ref> <ref>PMID:10952318</ref> <ref>PMID:11278922</ref> <ref>PMID:11604509</ref> <ref>PMID:12576485</ref> <ref>PMID:14645854</ref> <ref>PMID:14690608</ref> <ref>PMID:15045029</ref> <ref>PMID:15525518</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 17:
</div>
</div>
<div class="pdbe-citations 5oun" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5oun" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Helicase 3D structures|Helicase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 18824]]
 
-
[[Category: DNA helicase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Bragantini, B]]
+
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Charpentier, B]]
+
[[Category: Bragantini B]]
-
[[Category: Manival, X]]
+
[[Category: Charpentier B]]
-
[[Category: Quinternet, M]]
+
[[Category: Manival X]]
-
[[Category: Rouillon, C]]
+
[[Category: Quinternet M]]
-
[[Category: Atpase chaperon rvb1 rvb2 ruvbl1 ruvbl2 nmr snornp]]
+
[[Category: Rouillon C]]
-
[[Category: Hydrolase]]
+

Revision as of 10:24, 14 June 2023

NMR solution structure of the external DII domain of Rvb2 from Saccharomyces cerevisiae

PDB ID 5oun

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools