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| | ==A-ubiquitin like protein from the trypanosoma brucei== | | ==A-ubiquitin like protein from the trypanosoma brucei== |
| - | <StructureSection load='5zmb' size='340' side='right' caption='[[5zmb]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='5zmb' size='340' side='right'caption='[[5zmb]]' scene=''> |
| | == Structural highlights == | | == Structural highlights == |
| - | <table><tr><td colspan='2'>[[5zmb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Tryb2 Tryb2]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZMB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZMB FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5zmb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZMB FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tb927.6.3140 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=185431 TRYB2])</td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zmb OCA], [https://pdbe.org/5zmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zmb RCSB], [https://www.ebi.ac.uk/pdbsum/5zmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zmb ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zmb OCA], [http://pdbe.org/5zmb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zmb RCSB], [http://www.ebi.ac.uk/pdbsum/5zmb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zmb ProSAT]</span></td></tr> | + | |
| | </table> | | </table> |
| | + | == Function == |
| | + | [https://www.uniprot.org/uniprot/Q583M0_TRYB2 Q583M0_TRYB2] |
| | <div style="background-color:#fffaf0;"> | | <div style="background-color:#fffaf0;"> |
| | == Publication Abstract from PubMed == | | == Publication Abstract from PubMed == |
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| | __TOC__ | | __TOC__ |
| | </StructureSection> | | </StructureSection> |
| - | [[Category: Tryb2]] | + | [[Category: Large Structures]] |
| - | [[Category: Mi, J]] | + | [[Category: Trypanosoma brucei brucei TREU927]] |
| - | [[Category: Tu, X M]] | + | [[Category: Mi J]] |
| - | [[Category: Protein binding]] | + | [[Category: Tu XM]] |
| - | [[Category: Structure from cyana 3 0]]
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| Structural highlights
Function
Q583M0_TRYB2
Publication Abstract from PubMed
Ubiquitin-like proteins, similar to ubiquitin, can either exist freely or be covalently attached to other proteins via an enzymatic cascade. The ubiquitin-like proteins play roles in multiple biological processes including transcription, stress responses, DNA repair and so on. In this study, a novel ubiquitin-like protein (TbUbl11) was identified in Trypanosoma brucei. The solution structure of TbUbl11 was solved by NMR spectroscopy. TbUbl11 adopts a conserved beta-grasp fold composed by a five-stranded beta-sheet curling around a central alpha-helix, similar to other ubiquitin-like proteins. Meanwhile, some differences between TbUbl11 and other ubiquitin-like proteins were also identified. Additionally, we revealed that TbUbl11 is located in the whole cell body of procyclic-form T. brucei. This article is protected by copyright. All rights reserved.
Solution structure of a ubiquitin-like protein from Trypanosoma brucei.,Mi J, Zhang J, Liao S, Tu X Protein Sci. 2018 Jul 29. doi: 10.1002/pro.3492. PMID:30058168[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Mi J, Zhang J, Liao S, Tu X. Solution structure of a ubiquitin-like protein from Trypanosoma brucei. Protein Sci. 2018 Jul 29. doi: 10.1002/pro.3492. PMID:30058168 doi:http://dx.doi.org/10.1002/pro.3492
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