6gc3

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==Structure of Nrd1 CID - Sen1 NIM complex==
==Structure of Nrd1 CID - Sen1 NIM complex==
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<StructureSection load='6gc3' size='340' side='right'caption='[[6gc3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='6gc3' size='340' side='right'caption='[[6gc3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6gc3]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GC3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GC3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6gc3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GC3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GC3 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gc3 OCA], [http://pdbe.org/6gc3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gc3 RCSB], [http://www.ebi.ac.uk/pdbsum/6gc3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gc3 ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6gc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gc3 OCA], [https://pdbe.org/6gc3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6gc3 RCSB], [https://www.ebi.ac.uk/pdbsum/6gc3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6gc3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NRD1_YEAST NRD1_YEAST]] Plays a role in sequence-specific regulation of nuclear pre-mRNA abundance. [[http://www.uniprot.org/uniprot/SEN1_YEAST SEN1_YEAST]] ATP-dependent 5'->3' DNA/RNA helicase required for the expression and maturation of diverse classes of non-protein-coding RNAs like precursor tRNAs, rRNAs and small nuclear (snRNA) and nucleolar (snoRNA) RNAs. Directs RNA polymerase II transcription termination on snoRNAs as well as on several short protein-coding genes. May also play a role in transcription-coupled nucleotide excision repair.<ref>PMID:11565036</ref> <ref>PMID:15121901</ref> <ref>PMID:17157256</ref> <ref>PMID:8943355</ref> <ref>PMID:9365256</ref> <ref>PMID:9819377</ref>
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[https://www.uniprot.org/uniprot/NRD1_YEAST NRD1_YEAST] Plays a role in sequence-specific regulation of nuclear pre-mRNA abundance.
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Jasnovidova, O]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Kubicek, K]]
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[[Category: Jasnovidova O]]
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[[Category: Stefl, R]]
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[[Category: Kubicek K]]
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[[Category: Ctd-interacting domain]]
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[[Category: Stefl R]]
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[[Category: Helicase]]
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[[Category: Transcription]]
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[[Category: Transcription termination]]
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Revision as of 10:47, 14 June 2023

Structure of Nrd1 CID - Sen1 NIM complex

PDB ID 6gc3

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