6zv3

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==TFIIS N-terminal domain (TND) from human MED26==
==TFIIS N-terminal domain (TND) from human MED26==
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<StructureSection load='6zv3' size='340' side='right'caption='[[6zv3]], [[NMR_Ensembles_of_Models | 50 NMR models]]' scene=''>
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<StructureSection load='6zv3' size='340' side='right'caption='[[6zv3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6zv3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZV3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6zv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZV3 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zv3 OCA], [https://pdbe.org/6zv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zv3 RCSB], [https://www.ebi.ac.uk/pdbsum/6zv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zv3 ProSAT]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zv3 OCA], [https://pdbe.org/6zv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zv3 RCSB], [https://www.ebi.ac.uk/pdbsum/6zv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zv3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MED26_HUMAN MED26_HUMAN]] Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
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[https://www.uniprot.org/uniprot/MED26_HUMAN MED26_HUMAN] Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Veverka, V]]
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[[Category: Veverka V]]
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[[Category: Transcription]]
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[[Category: Transcription elongation]]
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Revision as of 11:09, 14 June 2023

TFIIS N-terminal domain (TND) from human MED26

PDB ID 6zv3

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