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5cr5
From Proteopedia
(Difference between revisions)
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<StructureSection load='5cr5' size='340' side='right'caption='[[5cr5]], [[Resolution|resolution]] 1.61Å' scene=''> | <StructureSection load='5cr5' size='340' side='right'caption='[[5cr5]], [[Resolution|resolution]] 1.61Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5cr5]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5cr5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CR5 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EL1:3-({(3R)-1-[(5-BROMOTHIOPHEN-2-YL)CARBONYL]PYRROLIDIN-3-YL}OXY)-N-METHYL-2-[(METHYLSULFONYL)AMINO]BIPHENYL-4-CARBOXAMIDE'>EL1</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EL1:3-({(3R)-1-[(5-BROMOTHIOPHEN-2-YL)CARBONYL]PYRROLIDIN-3-YL}OXY)-N-METHYL-2-[(METHYLSULFONYL)AMINO]BIPHENYL-4-CARBOXAMIDE'>EL1</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cr5 OCA], [https://pdbe.org/5cr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cr5 RCSB], [https://www.ebi.ac.uk/pdbsum/5cr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cr5 ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/BCAT2_HUMAN BCAT2_HUMAN] Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | + | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Somers | + | [[Category: Somers DO]] |
| - | + | ||
| - | + | ||
Current revision
X-RAY CRYSTAL STRUCTURE AT 1.61A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A BIPHENYL PYRROLIDINE ETHER COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR.
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