8slu

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'''Unreleased structure'''
 
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The entry 8slu is ON HOLD until Paper Publication
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==Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and high pressure (205 MPa)==
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<StructureSection load='8slu' size='340' side='right'caption='[[8slu]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
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Authors: Ebrahim, A., Guerrero, L., Riley, B.T., Kim, M., Huang, Q., Finke, A.D., Keedy, D.A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8slu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SLU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SLU FirstGlance]. <br>
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Description: Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and high pressure (205 MPa)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8slu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8slu OCA], [https://pdbe.org/8slu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8slu RCSB], [https://www.ebi.ac.uk/pdbsum/8slu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8slu ProSAT]</span></td></tr>
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[[Category: Finke, A.D]]
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</table>
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[[Category: Ebrahim, A]]
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== Function ==
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[[Category: Huang, Q]]
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[https://www.uniprot.org/uniprot/PTN5_HUMAN PTN5_HUMAN] May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.<ref>PMID:21777200</ref>
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[[Category: Keedy, D.A]]
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== References ==
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[[Category: Riley, B.T]]
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<references/>
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[[Category: Guerrero, L]]
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__TOC__
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[[Category: Kim, M]]
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Ebrahim A]]
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[[Category: Finke AD]]
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[[Category: Guerrero L]]
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[[Category: Huang Q]]
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[[Category: Keedy DA]]
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[[Category: Kim M]]
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[[Category: Riley BT]]

Revision as of 09:43, 21 June 2023

Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and high pressure (205 MPa)

PDB ID 8slu

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OCA

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