5d3o

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<StructureSection load='5d3o' size='340' side='right'caption='[[5d3o]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
<StructureSection load='5d3o' size='340' side='right'caption='[[5d3o]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5d3o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D3O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D3O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5d3o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5D3O FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLS, GLS1, KIAA0838 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5d3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d3o OCA], [https://pdbe.org/5d3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5d3o RCSB], [https://www.ebi.ac.uk/pdbsum/5d3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5d3o ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaminase Glutaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.2 3.5.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d3o OCA], [http://pdbe.org/5d3o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d3o RCSB], [http://www.ebi.ac.uk/pdbsum/5d3o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d3o ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN]] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.
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[https://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glutaminase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Huang, Q]]
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[[Category: Huang Q]]
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[[Category: Gac]]
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[[Category: Glutaminase c]]
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[[Category: Hydrolase]]
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Revision as of 10:20, 21 June 2023

Crystal structure of full length human glutaminase C expressed in E.coli

PDB ID 5d3o

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