5de3

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<StructureSection load='5de3' size='340' side='right'caption='[[5de3]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
<StructureSection load='5de3' size='340' side='right'caption='[[5de3]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5de3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlre Chlre]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DE3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5DE3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5de3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DE3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ARL3, CHLREDRAFT_128761 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3055 CHLRE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5de3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5de3 OCA], [https://pdbe.org/5de3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5de3 RCSB], [https://www.ebi.ac.uk/pdbsum/5de3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5de3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5de3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5de3 OCA], [http://pdbe.org/5de3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5de3 RCSB], [http://www.ebi.ac.uk/pdbsum/5de3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5de3 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ARL3_CHLRE ARL3_CHLRE]] Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Required for targeting proteins to the ciliary membrane by releasing myristoylated protein from unc119 cargo adapters into the cilium.[UniProtKB:P36405]
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[https://www.uniprot.org/uniprot/ARL3_CHLRE ARL3_CHLRE] Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Required for targeting proteins to the ciliary membrane by releasing myristoylated protein from unc119 cargo adapters into the cilium.[UniProtKB:P36405]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chlre]]
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[[Category: Chlamydomonas reinhardtii]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gotthardt, K]]
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[[Category: Gotthardt K]]
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[[Category: Lokaj, M]]
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[[Category: Lokaj M]]
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[[Category: Wittinghofer, A]]
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[[Category: Wittinghofer A]]
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[[Category: Adp ribosylation factor like]]
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[[Category: G-protein]]
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[[Category: Hydrolase]]
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Revision as of 10:31, 21 June 2023

The Crystal structure of Chlamydomonas reinhardtii Arl3 bound to GppNHp

PDB ID 5de3

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