5uii

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (21:22, 28 June 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5uii' size='340' side='right'caption='[[5uii]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
<StructureSection load='5uii' size='340' side='right'caption='[[5uii]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5uii]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UII OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5UII FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5uii]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UII FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BFR:N-butyl-N-(diaminomethylidene)guanidine'>BFR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.351&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5uih|5uih]], [[5uio|5uio]], [[5uip|5uip]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BFR:N-butyl-N-(diaminomethylidene)guanidine'>BFR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uii OCA], [https://pdbe.org/5uii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uii RCSB], [https://www.ebi.ac.uk/pdbsum/5uii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uii ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5uii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uii OCA], [http://pdbe.org/5uii PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uii RCSB], [http://www.ebi.ac.uk/pdbsum/5uii PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uii ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
+
[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
==See Also==
==See Also==
Line 16: Line 15:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Dihydrofolate reductase]]
+
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: London, R E]]
+
[[Category: London RE]]
-
[[Category: Pedersen, L C]]
+
[[Category: Pedersen LC]]
-
[[Category: Buformin]]
+
-
[[Category: Dhfr]]
+
-
[[Category: Nadp]]
+
-
[[Category: Oxidoreductase]]
+

Current revision

structure of DHFR with bound buformin and NADP

PDB ID 5uii

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools