7b2i

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Current revision (21:22, 28 June 2023) (edit) (undo)
 
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====
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==Heterodimeric tRNA-Guanine Transglycosylase from mouse==
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<StructureSection load='7b2i' size='340' side='right'caption='[[7b2i]]' scene=''>
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<StructureSection load='7b2i' size='340' side='right'caption='[[7b2i]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7b2i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B2I FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b2i OCA], [https://pdbe.org/7b2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b2i RCSB], [https://www.ebi.ac.uk/pdbsum/7b2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b2i ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b2i OCA], [https://pdbe.org/7b2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b2i RCSB], [https://www.ebi.ac.uk/pdbsum/7b2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b2i ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/QTRT2_MOUSE QTRT2_MOUSE] Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_03043]<ref>PMID:19414587</ref>
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==See Also==
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*[[TRNA-guanine transglycosylase 3D structures|TRNA-guanine transglycosylase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Mus musculus]]
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[[Category: Heine A]]
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[[Category: Reuter K]]
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[[Category: Sebastiani M]]

Current revision

Heterodimeric tRNA-Guanine Transglycosylase from mouse

PDB ID 7b2i

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