5dx6

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Current revision (22:04, 28 June 2023) (edit) (undo)
 
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<StructureSection load='5dx6' size='340' side='right'caption='[[5dx6]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='5dx6' size='340' side='right'caption='[[5dx6]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5dx6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DX6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DX6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5dx6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DX6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GY:3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-[(1R)-2-FLUORO-1-HYDROXYETHYL]-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM'>5GY</scene>, <scene name='pdbligand=65S:3-FLUORO-2-OXOPROPANOIC+ACID'>65S</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">budB, ilvK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GY:3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-[(1R)-2-FLUORO-1-HYDROXYETHYL]-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM'>5GY</scene>, <scene name='pdbligand=65S:3-FLUORO-2-OXOPROPANOIC+ACID'>65S</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetolactate_synthase Acetolactate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.6 2.2.1.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dx6 OCA], [https://pdbe.org/5dx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dx6 RCSB], [https://www.ebi.ac.uk/pdbsum/5dx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dx6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dx6 OCA], [http://pdbe.org/5dx6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dx6 RCSB], [http://www.ebi.ac.uk/pdbsum/5dx6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dx6 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ILVB_KLEPN ILVB_KLEPN]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Acetolactate synthase]]
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[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Andrews, F H]]
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[[Category: Andrews FH]]
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[[Category: Latta, A J]]
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[[Category: Latta AJ]]
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[[Category: McLeish, M J]]
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[[Category: McLeish MJ]]
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[[Category: Synthase thiamine diphosphate beta-fluoropyruvate]]
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[[Category: Transferase]]
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Current revision

Acetolactate Synthase from Klebsiella pneumoniae soaked with beta-fluoropyruvate

PDB ID 5dx6

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