7ybu

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Current revision (05:37, 5 July 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7ybu is ON HOLD until Paper Publication
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==Human propionyl-coenzyme A carboxylase==
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<StructureSection load='7ybu' size='340' side='right'caption='[[7ybu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors: Su, J.Y., Liu, D.S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7ybu]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YBU FirstGlance]. <br>
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Description: Human propionyl-coenzyme A carboxylase
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTI:5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL'>BTI</scene></td></tr>
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[[Category: Liu, D.S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ybu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ybu OCA], [https://pdbe.org/7ybu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ybu RCSB], [https://www.ebi.ac.uk/pdbsum/7ybu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ybu ProSAT]</span></td></tr>
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[[Category: Su, J.Y]]
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/PCCA_HUMAN PCCA_HUMAN] Defects in PCCA are the cause of propionic acidemia type I (PA-1) [MIM:[https://omim.org/entry/606054 606054]. PA-1 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.<ref>PMID:10101253</ref> <ref>PMID:12559849</ref> <ref>PMID:15059621</ref> <ref>PMID:10329019</ref>
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== Function ==
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[https://www.uniprot.org/uniprot/PCCA_HUMAN PCCA_HUMAN]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Liu DS]]
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[[Category: Su JY]]

Current revision

Human propionyl-coenzyme A carboxylase

PDB ID 7ybu

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