8a4x

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'''Unreleased structure'''
 
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The entry 8a4x is ON HOLD until Paper Publication
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==Crystal structure of human Cathepsin L with covalently bound Calpain inhibitor III==
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<StructureSection load='8a4x' size='340' side='right'caption='[[8a4x]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8a4x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A4X FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=L3F:(phenylmethyl)+N-[(2S)-3-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-phenyl-propan-2-yl]amino]butan-2-yl]carbamate'>L3F</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a4x OCA], [https://pdbe.org/8a4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a4x RCSB], [https://www.ebi.ac.uk/pdbsum/8a4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a4x ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chapman HN]]
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[[Category: Ewert W]]
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[[Category: Falke S]]
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[[Category: Guenther S]]
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[[Category: Hinrichs W]]
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[[Category: Karnicar K]]
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[[Category: Lieske J]]
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[[Category: Lindic N]]
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[[Category: Loboda J]]
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[[Category: Meents A]]
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[[Category: Reinke PYA]]
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[[Category: Sekirnik A]]
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[[Category: Turk D]]
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[[Category: Usenik A]]

Revision as of 05:39, 5 July 2023

Crystal structure of human Cathepsin L with covalently bound Calpain inhibitor III

PDB ID 8a4x

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