8dfz
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==NMR shows why a small chemical change almost abolishes the antimicrobial activity of GccF== | |
| - | + | <StructureSection load='8dfz' size='340' side='right'caption='[[8dfz]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8dfz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactiplantibacillus_plantarum Lactiplantibacillus plantarum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DFZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DFZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EW6:alpha-methyl-L-serine'>EW6</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | [[Category: Edwards | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dfz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dfz OCA], [https://pdbe.org/8dfz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dfz RCSB], [https://www.ebi.ac.uk/pdbsum/8dfz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dfz ProSAT]</span></td></tr> |
| - | [[Category: Harjes | + | </table> |
| - | [[Category: Norris | + | == Function == |
| + | [https://www.uniprot.org/uniprot/GCCF_LACPN GCCF_LACPN] Has antibacterial activity against L.plantarum ATCC 8014. In purified form, the activity is bacteriostatic (IC(50)=2 nM) rather than bactericidal.<ref>PMID:21251913</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Lactiplantibacillus plantarum]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Edwards PJB]] | ||
| + | [[Category: Harjes E]] | ||
| + | [[Category: Norris G]] | ||
Current revision
NMR shows why a small chemical change almost abolishes the antimicrobial activity of GccF
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