8j0q

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:47, 5 July 2023) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8j0q is ON HOLD until Paper Publication
+
==Structure of DNA binding domain of human TFAP2B==
-
 
+
<StructureSection load='8j0q' size='340' side='right'caption='[[8j0q]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
Authors: Liu, K., Xiao, Y.Q., Li, W.F., Min, J.R.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8j0q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8J0Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8J0Q FirstGlance]. <br>
-
Description: Structure of DNA binding domain of human TFAP2B
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-
[[Category: Xiao, Y.Q]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8j0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8j0q OCA], [https://pdbe.org/8j0q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8j0q RCSB], [https://www.ebi.ac.uk/pdbsum/8j0q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8j0q ProSAT]</span></td></tr>
-
[[Category: Min, J.R]]
+
</table>
-
[[Category: Li, W.F]]
+
== Disease ==
-
[[Category: Liu, K]]
+
[https://www.uniprot.org/uniprot/AP2B_HUMAN AP2B_HUMAN] Familial patent arterial duct;Char syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/AP2B_HUMAN AP2B_HUMAN] Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.<ref>PMID:11694877</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Li WF]]
 +
[[Category: Liu K]]
 +
[[Category: Min JR]]
 +
[[Category: Xiao YQ]]

Current revision

Structure of DNA binding domain of human TFAP2B

PDB ID 8j0q

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8j0q"
Personal tools