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8oza

From Proteopedia

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m (Protected "8oza" [edit=sysop:move=sysop])
Current revision (05:47, 5 July 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8oza is ON HOLD
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==Human cathepsin L in complex with covalently bound CA-074 methyl ester==
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<StructureSection load='8oza' size='340' side='right'caption='[[8oza]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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Authors: Falke, S., Lieske, J., Guenther, S., Ewert, W., Reinke, P.Y.A., Loboda, J., Karnicar, K., Usenik, A., Lindic, N., Sekirnik, A., Chapman, H.N., Hinrichs, W., Turk, D., Meents, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8oza]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OZA FirstGlance]. <br>
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Description: Human cathepsin L in complex with covalently bound CA-074 methyl ester
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3CN:3-AMINOPROPANE'>3CN</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=TPK:(1R)-1-[(2S)-PYRROLIDIN-2-YL]ETHANE-1,2-DIOL'>TPK</scene>, <scene name='pdbligand=WRH:(2~{S},3~{R})-2,3-bis(oxidanyl)butanedial'>WRH</scene></td></tr>
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[[Category: Hinrichs, W]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8oza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8oza OCA], [https://pdbe.org/8oza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8oza RCSB], [https://www.ebi.ac.uk/pdbsum/8oza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8oza ProSAT]</span></td></tr>
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[[Category: Sekirnik, A]]
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</table>
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[[Category: Ewert, W]]
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== Function ==
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[[Category: Chapman, H.N]]
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[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.
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[[Category: Lindic, N]]
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__TOC__
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[[Category: Karnicar, K]]
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</StructureSection>
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[[Category: Loboda, J]]
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[[Category: Homo sapiens]]
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[[Category: Lieske, J]]
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[[Category: Large Structures]]
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[[Category: Usenik, A]]
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[[Category: Synthetic construct]]
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[[Category: Meents, A]]
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[[Category: Chapman HN]]
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[[Category: Turk, D]]
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[[Category: Ewert W]]
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[[Category: Falke, S]]
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[[Category: Falke S]]
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[[Category: Guenther, S]]
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[[Category: Guenther S]]
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[[Category: Reinke, P.Y.A]]
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[[Category: Hinrichs W]]
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[[Category: Karnicar K]]
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[[Category: Lieske J]]
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[[Category: Lindic N]]
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[[Category: Loboda J]]
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[[Category: Meents A]]
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[[Category: Reinke PYA]]
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[[Category: Sekirnik A]]
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[[Category: Turk D]]
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[[Category: Usenik A]]

Current revision

Human cathepsin L in complex with covalently bound CA-074 methyl ester

PDB ID 8oza

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