5e5m

<StructureSection load='5e5m' size='340' side='right'caption='[[5e5m]], [[Resolution|resolution]] 2.18&Aring;' scene=''>

<table><tr><td colspan='2'>[[5e5m]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelidae Camelidae] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E5M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E5M FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.182&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e5m OCA], [https://pdbe.org/5e5m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e5m RCSB], [https://www.ebi.ac.uk/pdbsum/5e5m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e5m ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/CTLA4_MOUSE CTLA4_MOUSE] Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28 (By similarity).

 

[[Category: Camelidae]]

[[Category: Large Structures]]

[[Category: Mus musculus]]

[[Category: Almo SC]]

[[Category: Bonanno JB]]

[[Category: Fedorov AA]]

[[Category: Fedorov EV]]

[[Category: Samanta D]]