5ec4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='5ec4' size='340' side='right'caption='[[5ec4]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
<StructureSection load='5ec4' size='340' side='right'caption='[[5ec4]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5ec4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EC4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EC4 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5ec4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EC4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EC4 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5LQ:5-(3-CHLOROPHENYL)-4-METHYL-~{N}-(3-MORPHOLIN-4-YLPROPYL)-1,1-BIS(OXIDANYLIDENE)-1,2-THIAZOL-3-AMINE'>5LQ</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.21&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ebv|5ebv]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5LQ:5-(3-CHLOROPHENYL)-4-METHYL-~{N}-(3-MORPHOLIN-4-YLPROPYL)-1,1-BIS(OXIDANYLIDENE)-1,2-THIAZOL-3-AMINE'>5LQ</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eis, Rv2416c, MTCY253.04 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ec4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ec4 OCA], [https://pdbe.org/5ec4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ec4 RCSB], [https://www.ebi.ac.uk/pdbsum/5ec4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ec4 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ec4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ec4 OCA], [http://pdbe.org/5ec4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ec4 RCSB], [http://www.ebi.ac.uk/pdbsum/5ec4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ec4 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU]] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref>
+
[https://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 25: Line 24:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Myctu]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Gajadeera, C S]]
+
[[Category: Gajadeera CS]]
-
[[Category: Garneau-Tsodikova, S]]
+
[[Category: Garneau-Tsodikova S]]
-
[[Category: Hou, C]]
+
[[Category: Hou C]]
-
[[Category: Tsodikov, O V]]
+
[[Category: Tsodikov OV]]
-
[[Category: Aminoglycoside]]
+
-
[[Category: Resistance]]
+
-
[[Category: Transferase]]
+
-
[[Category: Transferase-transferase inhibitor complex]]
+
-
[[Category: Tuberculosis]]
+

Revision as of 06:20, 5 July 2023

Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 13g and CoA

PDB ID 5ec4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5ec4"
Personal tools