5ei5

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<StructureSection load='5ei5' size='340' side='right'caption='[[5ei5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='5ei5' size='340' side='right'caption='[[5ei5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ei5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EI5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ei5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetronarce_californica Tetronarce californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EI5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=03S:METHANESULFONIC+ACID'>03S</scene>, <scene name='pdbligand=AA7:N,N-DI-1,2,3,4-TETRAHYDROACRIDIN-9-YLHEPTANE-1,7-DIAMINE'>AA7</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=03S:METHANESULFONIC+ACID'>03S</scene>, <scene name='pdbligand=AA7:N,N-DI-1,2,3,4-TETRAHYDROACRIDIN-9-YLHEPTANE-1,7-DIAMINE'>AA7</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ei5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ei5 OCA], [https://pdbe.org/5ei5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ei5 RCSB], [https://www.ebi.ac.uk/pdbsum/5ei5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ei5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ei5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ei5 OCA], [https://pdbe.org/5ei5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ei5 RCSB], [https://www.ebi.ac.uk/pdbsum/5ei5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ei5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ACES_TORCA ACES_TORCA]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
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[https://www.uniprot.org/uniprot/ACES_TETCF ACES_TETCF] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Acetylcholinesterase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Torpedo californica]]
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[[Category: Tetronarce californica]]
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[[Category: Lamba, D]]
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[[Category: Lamba D]]
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[[Category: Pesaresi, A]]
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[[Category: Pesaresi A]]
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[[Category: Alpha beta hydrolase]]
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[[Category: Hydrolase]]
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[[Category: Irreversible inhibitor]]
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Revision as of 06:29, 5 July 2023

Crystal structure of MSF-aged Torpedo californica Acetylcholinesterase in complex with alkylene-linked bis-tacrine dimer (7 carbon linker)

PDB ID 5ei5

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