3o8y

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<StructureSection load='3o8y' size='340' side='right'caption='[[3o8y]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
<StructureSection load='3o8y' size='340' side='right'caption='[[3o8y]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3o8y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O8Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O8Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3o8y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O8Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O8Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.389&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ALOX5, LOG5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Arachidonate_5-lipoxygenase Arachidonate 5-lipoxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.34 1.13.11.34] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o8y OCA], [https://pdbe.org/3o8y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o8y RCSB], [https://www.ebi.ac.uk/pdbsum/3o8y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o8y ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o8y OCA], [https://pdbe.org/3o8y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o8y RCSB], [https://www.ebi.ac.uk/pdbsum/3o8y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o8y ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LOX5_HUMAN LOX5_HUMAN]] Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.<ref>PMID:21233389</ref>
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[https://www.uniprot.org/uniprot/LOX5_HUMAN LOX5_HUMAN] Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.<ref>PMID:21233389</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arachidonate 5-lipoxygenase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bartlett, S G]]
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[[Category: Bartlett SG]]
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[[Category: Boeglin, W E]]
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[[Category: Boeglin WE]]
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[[Category: Brash, A R]]
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[[Category: Brash AR]]
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[[Category: Gilbert, N C]]
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[[Category: Gilbert NC]]
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[[Category: Neau, D B]]
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[[Category: Neau DB]]
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[[Category: Newcomer, M E]]
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[[Category: Newcomer ME]]
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[[Category: Waight, M T]]
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[[Category: Waight MT]]
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[[Category: Coactosin like protein]]
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[[Category: Cytosol]]
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[[Category: Dioxygenase]]
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[[Category: Five lipoxygenase activating protein]]
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[[Category: Lox]]
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[[Category: Nuclear membrane]]
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[[Category: Oxidoreductase]]
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[[Category: Plat]]
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Revision as of 07:58, 12 July 2023

Stable-5-Lipoxygenase

PDB ID 3o8y

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